Often, these are prescribed for chest pain called angina. Common ones include: Flushing of the skin. You can take this medicine with or without food 30 minutes before sex, depending on the dose. Its effects might last longer if you have mild to moderate ED. This medication is taken with or without food an hour before sex.Oral medicines for ED usually work well and cause few side effects. The four main medicines taken by mouth for erectile dysfunction are: Avanafil (Stendra). Sildenafil (Viagra). Tadalafil (Cialis). Vardenafil. These medicines are called PDE5 inhibitors. What’s the best Viagra for men? In truth, there’s only one Viagra. That’s Pfizer’s drug powered by the active ingredient Sildenafil. It comes in 25mg, 50mg, and mg doses. Some men might find that the best treatment for erectile dysfunction (ED) is generic . Which erectile dysfunction pill – Viagra, Cialis, Levitra, Stendra – is right for you? Here’s what’s what with all the options, including money-saving generics.