If you have any doubts about your medication, we strongly recommend you to see a doctor immediately. Importantly, clear evidence was found for improvements in interpersonal relationships, suggesting that both sexual partners benefitted from dapoxetine treatment. When administered, this drug blocks the serotonin transporter, which modulates the reflex that triggers ejaculation. For these reasons, before you start taking dapoxetine it is important that your doctor knows: If you have a tendency to faint. Satisfaction with sexual intercourse Changes from baseline in satisfaction with sexual intercourse were reported in eight studies Table 3. If you have ever had an allergic reaction to a medicine.Dapoxetine is primarily used in the treatment of sexual dysfunctions like premature ejaculation. What Are the Contraindications of Dapoxetine? Dapoxetine is . Description. Dapoxetine is a medicine used for the treatment of premature ejaculation (a sexual dysfunction in which a man ejaculates too quickly during sexual . Anxiety; asthenia; concentration impaired; constipation; diarrhoea; dizziness; drowsiness; dry mouth; gastrointestinal discomfort; gastrointestinal disorders; headache; .