What are the side effects of erectile dysfunction medications? Most erectile dysfunction medications belong to the drug class known as PDE5 inhibitors , which help relax the muscles and increase blood flow to allow for a full erection. Medical consultations were also taken into consideration, as PDE5 inhibitors require a valid prescription from a licensed medical provider. Most companies have an FAQ or shipping policy page you can reference to learn whether discreet packaging is available. What is the safest drug for erectile dysfunction?Boasts a Wide Range of ED Medications. Hims offers ED medications with three main active ingredients (sildenafil, tadalafil, vardenafil).Missing: walmart. Looking to overcome erectile dysfunction problems? We reviewed and compared prices, insurance coverage, and safety from the best online ED prescription . Pros Convenience: Hims takes customers from assessment to purchase in a single online process. Range of products: Hims provides various products for a range of /5.