FDA encourages anyone aware of a serious side effect, including consumers or patients, to make a MedWatch report. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. Tadalafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow more easily. Benign prostatic hypertrophy is a condition in which the prostate gland becomes enlarged, obstructing the free flow of urine. If you are thinking about using tadalafil please discuss it with your doctor. You should take tadalafil one time a day. The decision of availability is completely up to the company marketing the product.from $2, for 30 tablets Cialis Coupons, Copay Cards and Rebates Cialis offers may take the form of printable coupons, rebates, savings or copay cards, trial offers, or free . How Cialis Works. Tadalafil and other PDE5 inhibitors primarily work by inducing muscle relaxation. Tadalafil stops the breakdown of a chemical responsible for relaxing muscles. In ED and PAH, the drug targets muscle cells in blood vessels. When the blood vessel muscle cells relax, this expands the vessel and increases blood flow; this . Cialis (tadalafil), for instance, is one of the most popular brand-name ED medications, and it is manufactured by Eli Lilly. Cialis can cost around $ to $ per month out of pocket, depending on the dosage you need. The first generic version of Cialis was released in October , and other manufacturers have released generic versions .