This medicine also works best when you take it an hour before sex on an empty stomach. Yes, ED pills can cause side effects. However, others work on a cash-pay basis and don’t partner with insurance companies. You can take this medicine with or without food 30 minutes before sex, depending on the dose. Side effects Side effects of oral ED medicines are often mild.Sildenafil (Viagra) is a phosphodiesterase-5 (PDE-5) inhibitor. PDE-5 is a protein in your body that breaks down the molecules that normally cause an erection. When it blocks . Best for generic Viagra and other health and wellness medications: Lemonaid Sildenafil. Best. Depending on your symptoms and needs, you may be prescribed Viagra, sildenafil, Cialis, tadalafil, Stendra, paroxetine, or a combination of tadalafil and sildenafil, available as .

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