How oral medicines differ Each oral medicine for ED has a slightly different chemical makeup. These include a heart attack, stroke or a serious heart rhythm disorder in the past six months. The mechanism of action for ED pills is simple: They inhibit the PDE5 enzyme which regulates the signals responsible for the smooth muscle tissue. This medicine works best when you take it on an empty stomach an hour before sex. It’s available in 10 mg and 20 mg tablets. You can take this medicine with or without food 30 minutes before sex, depending on the dose. Online pharmacies can be broadly categorized as: Mail-order pharmacies are operated by pharmacy benefits managers PBMs on behalf of health insurers or providers.It’s no longer sold under the brand name Levitra, but it’s available as generic tablets and orally disintegrating tablets (ODTs). Common side effects of vardenafil include . AdGet a Prescription for ED treatment, discreetly deliverED to your door.4/5 ( reviews)Types: Finasteride · Tadalafil · Sildenafil. AdFind the Lowest Price for Your Prescription Meds and Save at Your Local Pharmacy Today! Over 50K Customers Save on Prescriptions Each Week Using Free SingleCare® Discount Cards/5 (2, reviews)Site visitors: Over K in the past month.