Cialis Daily tadalafil : This low-dose Cialis works by increasing blood flow to the penis over time, making it easier to have an erection when aroused. In addition, consider the information below. It may be difficult to remain firm despite wanting to have sex. National Library of Medicine. Tadalafil may not be safe for people with certain medical conditions, including people who have had a stroke , have coronary heart disease or retinitis pigmentosa an eye disease.Dosage range: mg to 5 mg. Frequency: once daily, regardless of the timing of sexual activity. Cialis’s recommended dosage when it’s taken as needed for ED is as follows. Dosage range: 5 mg to 20 mg. Frequency: one dose at least 30 minutes before sexual activity, with a maximum of one dose per day*. MNT ‘s review At Hims, Cialis is available as: Daily tadalafil: or 5 mg daily pill Tadalafil: 5 mg, 10 mg, or 20 mg, taken as needed Cialis: mg, 5 mg, 10 mg, and 20 mg, taken .  · But on average, its effects start to lessen 2 to 3 hours after you take a dose. The typical dose for once-daily Cialis for ED is milligrams (mg) to 5 mg. When used as needed for ED, the usual.