In , the Phase 2 clinical studies were initiated for males experiencing ED, then progressed to the Phase 3 trials that supported the drug’s FDA approval. What side effects can this medication cause? Tadalafil Adcirca is used to improve the ability to exercise in people with pulmonary arterial hypertension PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness. Integrated analysis of 11 tadalafil trials concluded that tadalafil is a very effective and well tolerated treatment for ED. Embracing the Future with Cialis The transformative power of Cialis extends far beyond its traditional uses.Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men. What is the price of Cialis? The price you pay for Cialis can vary. Your cost may depend on your treatment plan, your insurance coverage (if you have it), and the . heart attack symptoms – chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating. Common tadalafil side effects may include: headache; flushing (warmth, redness, or tingly feeling); nausea, upset stomach; stuffy nose; or. muscle pain, back pain, pain in your arms, legs, or back. This is not a complete list of side.