Often, these are prescribed for chest pain called angina. Talk with your healthcare provider about which might be best for you. Avanafil Stendra. When choosing one, tell your doctor or other health care professional what your preferences are, such as cost, ease of use, how long the drug’s effects last and side effects. This boosts blood flow and helps you get an erection from sexual activity. Emling S. These include itraconazole Sporanox, Tolsura , ketoconazole Extina, Ketozole, others and ritonavir Norvir.(1) One difference is that tadalafil (Cialis) is approved to treat both ED and BPH whereas sildenafil (Viagra) can only be used for ED. (2) Another difference is that . Cons can cause headaches and muscle aches must be swallowed whole can cause indigestion can make you appear flushed not available over-the-counter (OTC) . 1. It Targets the Problem and Works Quickly. Being a topical means MED targets your penis directly and offers a “quick onset of action,” Dr. Pearlman .